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Assessment
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Development and Validation of the HIV Medication Readiness Scale

Louise Balfour

Ottawa Hospital-General Campus, lbalfour{at}ottawahospital.on.ca, University of Ottawa, Ottawa Health Research Institute

Giorgio A. Tasca

Ottawa Hospital-General Campus, University of Ottawa, Ottawa Health Research Institute, Carleton University

John Kowal

Ottawa Hospital-General Campus

Kimberly Corace

Ottawa Hospital-General Campus, University of Ottawa

Curtis L. Cooper

Ottawa Hospital-General Campus, University of Ottawa

Jonathan B. Angel

Ottawa Hospital-General Campus, University of Ottawa

Gary Garber

Ottawa Hospital-General Campus, University of Ottawa

Paul A. MacPherson

Ottawa Hospital-General Campus, University of Ottawa

D. William Cameron

Ottawa Hospital-General Campus, University of Ottawa

Excellent medication adherence (>95%) is required for optimal HIV treatment success. This study aimed to develop and validate a brief scale to assess psychological readiness for successfully starting and adhering to HIV medications. HIV-positive men and women (N = 142) from an HIV outpatient clinic completed the proposed HIV Medication Readiness Scale (HMRS) prior to starting HIV medications. The 10-item HMRS demonstrated high internal consistency (alpha = .90), test-retest reliability (r = .83), and sensitivity to change following a standardized 4-session psychoeducational intervention designed to increase readiness for successful adherence. Predictive validity was supported by higher readiness scores on the day starting HIV medications, predicting higher treatment adherence at 1-month follow-up. The HMRS is a brief, easy-to-use, clinically relevant tool that can assist in identifying people living with HIV at high risk of nonadherence, who might benefit from tailored readiness counseling prior to initiating HIV medications.

Key Words: medication readiness • adherence • HAART • HIV • psychometric evaluation

References

  • Balfour, L., Kowal, J., Silverman, A., Tasca, G.A., Angel, J.B., MacPherson, P.A., et al. (2006). A randomized controlled psycho-education intervention trial: Improving psychological readiness for successful HIV medication adherence and reducing depression before initiation HAART. AIDS Care, 18, 830-838.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Bangsberg, D.R., Hecht, F.M., Charlebois, E.D., Zolopa, A.R., Holodniy, M., Sheiner, L., et al. (2000). Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS, 14, 357-366.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Boden, D., Hurley, A., Zhang, L., Cao, Y., Guo, Y., Jones, E., et al. (1999). HIV-1 drug resistance in newly infected individuals. JAMA, 282, 1135-1141.[Abstract/Free Full Text]
  • Chesney, M.A., Ickovics, J.R., Chambers, D.B., Gifford, A.L., Neidig, J., & Zwick, D.B.B. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. AIDS Care, 12, 255-266.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Cronbach, L.J. (1951). Coefficient alpha and the internal structure of tests. Psychometrika, 16, 297-334.[CrossRef][Web of Science]
  • Clark, L.A., & Watson, D. (1995). Constructing validity: Basic issues in objective scale development. Psychological Assessment, 7, 309-319.[CrossRef][Web of Science]
  • Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155-159.[CrossRef][Medline] [Order article via Infotrieve]
  • DiMatteo, M.R., Hays, R.D., & Sherbourne, C.D. (1992). Adherence to cancer regimens: Implications for treating the older patient. Oncology, 6, 50-57.[CrossRef][Medline] [Order article via Infotrieve]
  • DiMatteo, M.R., Sherbourne, C.D., Hays, R.D., Ordway, L., Kravitz, R.L., McGlynn, E.A., et al. (1993). Physicians' characteristics influence patients' adherence to medical treatment: Results from the medical outcomes study. Health Psychology, 12, 93-102.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Dobkin, P.L., Sita, A., & Sewitch, M.J. (2006). Predictors of adherence to treatment in women with fibromyalgia. Clinical Journal of Pain, 22, 286-294.
  • Enriquez, M., Gore, P.A., O'Connor, M.C., & McKinsey, D.S. (2004). Assessment of readiness for adherence by HIV-positive males who had previously failed treatment. Journal of the Association of Nurses in AIDS Care, 15, 42-49.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Enriquez, M., Lackey, N.R., O'Connor, M.C., & McKinsey, D.S. (2004). Successful adherence after multiple HIV treatment failures. Journal of Advanced Nursing, 45, 438-446.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Fisher, J.D., & Fisher, W.A. (1992). Changing AIDS-risk behavior. Psychological Bulletin, 111, 455-474.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Fisher, J.D., & Fisher, W.A. (2000). Theoretical approaches to individual-level change. In J. Peterson & R. DiClemente (Eds.), HIV prevention handbook (pp. 3-55). New York: Kluwer Academic.
  • Fisher, J.D., & Fisher, W.A. (2002). The information-motivation-behavioral skills model. In R. DiClemente, R. Crosby, & M. Kegler (Eds.), Emerging promotion research and practice (pp. 40-70). San Francisco: Jossey-Bass.
  • Fleury, J. (1991). The qualitative generation of wellness motivation theory. Nursing Research, 40, 286-291.[Web of Science][Medline] [Order article via Infotrieve]
  • Fleury, J. (1994). The index of readiness: Development and psychometric analysis. Journal of Nursing Measurement, 2, 143-154.[Medline] [Order article via Infotrieve]
  • Fowler, M.E. (1998). Recognizing the phenomenon of readiness: Concept analysis and case study. Journal of the Association of Nurses in AIDS Care, 9, 72-76.[Medline] [Order article via Infotrieve]
  • Geller, J., Cockell, S.J., & Drab, D.L. (2001). Assessing readiness for change in the eating disorders: The psychometric properties of the readiness and motivation interview. Psychological Assessment, 13, 189-198.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Gross, R., Yip, B., Re, V.L., Wood, E., Alexander, C.S., Harrigan, P.R., et al. (2006). A simple, dynamic measure of antiretroviral therapy adherence predicts failure to maintain HIV-1 suppression. Journal of Infectious Diseases, 194, 1108-1114.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Hamilton, G.A. (2003). Measuring adherence in a hypertension clinical trial. European Journal of Cardiovascular Nursing, 2, 219-228.
  • Hays, R.D., & DiMatteo, M.R. (1987). Key issues and suggestions for patient compliance assessment: Sources of information, focus of measures, and nature of response options. Journal of Compliance in Health Care, 2, 37-53.
  • Highstein, G.R., Willey, C., & Mundy, L.M. (2006). Development of stage of readiness and decisional balance instruments: Tools to enhance clinical decision-making for adherence to antiretroviral therapy. AIDS and Behavior, 10, 563-573.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Kennedy, S.B. (2000). Developing a self-administered tool to predict adherence to antiretroviral therapy: Design, method, and objectives. AIDS Patient Care & STDs, 14, 309-316.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Llabre, M., Weaver, K.E., Duran, R.E., Antoni, M.J., McPherson-Baker, S., & Schneiderman, N. (2006). A measurement model of medication adherence to highly active antiretroviral therapy and its relation to viral load in HIV-positive adults. AIDS Patient Care and STDs, 10, 701-711.
  • McCusker, J., Bigelow, C., Frost, R., Hindin, R., Vickers-Lahti, M., & Zorn, M. (1994). The relationships of HIV status and HIV risky behavior with readiness for treatment. Drug and Alcohol Dependence, 34, 129-138.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Miller, L., & Hays, R. (2000). Measuring adherence to antiretroviral medications in clinical trials. HIV Clinical Trials, 1, 36-46.
  • Morgenstern, T.T., Grimes, D.E., & Grimes, R.M. (2002). Assessment of readiness to initiate antiretroviral therapy. HIV Clinical Trials, 3, 168-172.
  • Murphy, D.A., Wilson C.M., Durako, S.J., Muenz, L.R., & Belzer, M. (2001). Antiretroviral medication adherence among the REACH HIV-infected adolescent cohort. AIDS Care, 13, 27-40.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • New York State Department of Health AIDS Institute's Clinical Guidelines Development Program. (2006). Antiretroviral therapy. Retrieved November 17, 2006, from http://www.hivguidelines.org/GuideLine.aspx?pageID=257&guideLineID=10&vType=txt
  • Nordqvist, O., Sodergard, B., Tully, M.P., Sonnerborg, A., & Lindblad, A.K. (2006). Assessing and achieving readiness to initiate HIV medication. Patient Education and Counseling, 62, 21-30.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Nunnally, J.C., & Bernstein, I.H. (1994). Psychometric theory. New York: McGraw-Hill.
  • Paterson, D.L., Swindells, S., Mohr, J., Brester, M., Vergis, E.N., Squier, C., et al. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133, 21-30.[Abstract/Free Full Text]
  • Prochaska, J.O., & DiClemente, C.C. (1986). Toward a comprehensive model of change. In W. R. Miller & N. Heather (Eds.), Treating addictive behaviors: Processes of change (pp. 3-27). New York: Plenum.
  • Prochaska, J.O., & Velicer, W.F. (1997). The transtheoretical model of health behavior change. American Journal of Health Promotion, 12, 38-48.[Web of Science][Medline] [Order article via Infotrieve]
  • Putnam, D.E., Finney, J.W., Barkley, P.L., & Bonner, M.J. (1994). Enhancing commitment improves adherence to a medical regimen. Journal of Consulting & Clinical Psychology, 62, 191-194.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Reynolds, N.R., & Neidig, J.L. (2002). Characteristics of nausea reported by HIV-infected patients initiating combination antiretroviral regimens. Clinical Nursing Research, 11, 71-88.[Abstract/Free Full Text]
  • Reynolds, N.R., Testa, M.A., Marc, L.G., Chesney, M.A., Neidig, J.L., Smith, S.R., et al. (2004). Factors influencing medication adherence beliefs and self-efficacy in persons naïve to antiretroviral therapy: A multicenter, cross-sectional study. AIDS and Behavior, 8, 141-150.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Riley, T.A., & Fava, J.L. (2003). Stress and transtheoretical model indicators of stress management behaviors in HIV-positive women. Journal of Psychosomatic Research, 54, 245-252.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Roberts, K.J. (2000). Barriers to and facilitators of HIV-positive patients' adherence to antiretroviral treatment regimens. AIDS Patient Care & STDs, 14, 155-168.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Rosenstock, I.M. (1974). Historical origins of the health belief model. Health Education Monographs, 2, 328-335.[Web of Science]
  • Rusbult, C.E. (1980). Commitment and satisfaction in romantic associations: A test of the investment model. Journal of Experimental Social Psychology, 16, 172-186.[CrossRef][Web of Science]
  • Safren, S.A., Otto, M.W., & Worth, J.L. (1999). Life-steps: Applying cognitive behavioral therapy to HIV medication adherence. Cognitive and Behavioral Practice, 6, 332-341.[CrossRef]
  • Safren, S.A., Otto, M.W., Worth, J.L., Salomon, E., Johnson, W., Mayer, K., et al. (2001). Two strategies to increase adherence to antiretroviral medication: Life-steps and medication monitoring. Behaviour Research & Therapy, 39, 1151-1162.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Sherbourne, C.D., Hays, R.D., Ordway, L., DiMatteo, M.R., & Kravitz, R.L. (1992). Antecedents of adherence to medical recommendations: Results from the medical outcomes study. Journal of Behavioral Medicine, 15, 447-468.
  • Shet, A., Berry, L., Mohri, H., Mehandru, S., Chung, C., Kim, A., et al. (2006). Tracking the prevalence of transmitted antiretroviral drug-resistant HIV-1: A decade of experience. Journal of Acquired Immune Deficiency Syndromes, 41, 439-446.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Simoni, J.M., Kurth, A.E., Pearson, C.R., Pantalone, D.W., Merrill, J.O., & Frick, P.A. (2006). Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management. AIDS & Behavior, 10, 227-245.[CrossRef]
  • Starace, F., Massa, A., Amico, K.R., & Fisher, J.D. (2006). Adherence to antiretroviral therapy: An empirical test of the information-motivation-behavioral skills model. Health Psychology, 25, 153-162.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Stevens, J.P. (2002). Applied multivariate statistics for the social sciences (4th ed.). Mahwah, NJ: Lawrence Erlbaum.
  • Wagner, G.J. (2002). Predictors of antiretroviral adherence as measured by self-report, electronic monitoring, and medication diaries. AIDS Patient Care & STDs, 16, 599-608.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Wagner, G.J., & Ryan, G.W. (2005). Hepatitis C virus treatment decision-making in the context of HIV co-infection: The role of medical, behavioral and mental health factors in assessing treatment readiness. AIDS, 19, 190-198.
  • Walsh, J.C., Mandalia, S., & Gazzard, B. (2002). Responses to a 1 month self-report on adherence to antiretroviral therapy are consistent with electronic data and virological treatment outcome. AIDS, 16, 269-277.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Weiss, L., French, T., Finkelstein, R., Waters, M., Mukherjee, R., & Agins, B. (2003). HIV-related knowledge and adherence to HAART. AIDS Care, 15, 673-679.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Willey, C., Redding, C., Stafford, J., Garfield, F., Geletko, S., Flanigan, T., et al. (2000). Stages of change for adherence with medication regimens for chronic disease: Development and validation of a measure. Clinical Therapeutics, 22, 858-871.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]

Assessment, Vol. 14, No. 4, 408-416 (2007)
DOI: 10.1177/1073191107304295
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