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Construct Validity of Neuropsychological Tests in Schizophrenia

Daniel N. Allen

Felito Aldarondo

Gerald Goldstein

Stephen G. Huegel

VA Pittsburgh Healthcare System, PA

Mark Gilbertson

VA Medical Center Manchester, NH

Daniel P. Van Kammen

The Robert Wood Johnson Pharmaceutical Research Institute, NJ

Validity studies of neuropsychological tests have typically examined individuals with neurological disorders. The present study was designed to investigate the construct validity of neuropsychological measures in patients with schizophrenia. We used Wechsler Adult Intelligence Scale-Revised (WAIS-R) factor scores that were generated from the population of interest as marker variables in the present analysis. The current study included 39 patients with schizophrenia who were evaluated with a battery of neuropsychological tests assessing attention, memory, and abstract reasoning abilities. Pearson correlations indicated significant relationships between (a) WAIS-R Verbal Comprehension factor and tests of sustained attention, verbal memory and remote memory; (b) WAIS-R Perceptual Organization factor and tests of visual memory and abstraction and problem solving; and (c) WAIS-R Freedom From Distractibility factor and neuropsychological measures of attention and concentration. These results provide support for the construct validity of the neuropsychological tests in patients with schizophrenia, and indicate that these tests evaluate essentially the same constructs in patients with schizophrenia as they do for patients with structural neurological disorders.

Key Words: Schizophrenia • neuropsychological tests • WAIS-R • WMS-R • WCST • CPT

Assessment, Vol. 5, No. 4, 365-374 (1998)
DOI: 10.1177/107319119800500406
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D. Dickinson, V. N. Iannone, and J. M. Gold
Factor Structure of the Wechsler Adult Intelligence Scale-III in Schizophrenia
Assessment, June 1, 2002; 9(2): 171 - 180.
[Abstract] [PDF]